You can confidently administer RUCONEST after training
RUCONEST is portable and can be self-administered after training*
Prior to reconstitution RUCONEST does not need to be refrigerated
After reconstitution, RUCONEST is injected over 5 minutes with a small butterfly needle
Keep refrigerated for up to 8 hours after reconstitution and discard partially used vials
*Initial training will be under the supervision of an HCP experienced in the treatment of HAE.
†Data from 601 patients using RUCONEST show that 85% of patients trained felt confident, mostly confident, or extremely confident on a Likert scale of 1-5 in terms of their ability to self-infuse.
When it comes to administration, confidence matters. Be sure to read the full instructions, located in the Prescribing Information under the Patient Product Information section, before preparing the medication for injection.
A dedicated RUCONEST Patient Advocate is available to you for in-person training, as many times as needed.
Tips to ensure optimal vein health for patients self-administering RUCONEST
RUCONEST can be self-administered by appropriately trained patients, so it's important that you do everything you can to take care of your veins. Below are some tips to help keep your veins healthy and viable.
Vein Care Dos:
Find a well-lit area to do your infusion
Make sure to alternate arms when infusing your RUCONEST doses
When choosing a vein, look for one that feels bouncy, not stiff or rolling!
Use a tourniquet to apply pressure and help your vein become more prominent for easier access
Stay hydrated
Vein Care Don'ts:
Don't rush. Staying calm will help you to easily access your veins
Don't use veins that are red, inflamed, or sore to touch
Don't forget to remove the tourniquet — leaving it on for a long time may cause damage to your veins
Important Note: Veins that are red or inflamed may be a sign of infection. Infusing with an infected vein may cause permanent damage. Talk to your healthcare provider about what you can do to treat red or inflamed veins.
RUCONEST dosing and administration
Recommended dose of RUCONEST for a HAE swell
Discuss dosing with your healthcare provider to help ensure that the correct dose of RUCONEST is administered.
Dosing by body weight
Body weighta
RUCONEST dose for IV injection
Volume (mL) of reconstituted solution (150 U/mL) to be administered
<84 kg (~185 lb)
50 U per kg
Body weight in kg divided by 3
≥84 kg (~185 lb)
4200 U (2 vials)
28 mL
a1 kg=2.2 lb
RUCONEST is administered by slow intravenous (IV) injection over approximately 5 minutes
Patients may self-administer RUCONEST after receiving appropriate training by a qualified healthcare professional
RUCONEST should be administered upon recognition of an HAE swell
Reconstitute each vial (2100 U) by adding 14 mL sterile water for injection per vial to obtain a solution of 150 U per mL
Why RUCONEST?
RUCONEST is a plasma-free C1-INH proven to help treat HAE attacks.
Some insurance companies are instituting new policies called accumulator adjustment programs and/or maximizer programs. These can affect your participation in the RUCONEST Patient Savings Program.
Accumulator Adjustment Programs are when your insurance plan does not apply the RUCONEST Patient Savings Program to satisfy your co-payment, deductible, or co-insurance for RUCONEST.
Co-pay Maximizer Programs are when your insurance company requires you to enroll in the RUCONEST Patient Savings Program as a condition of your plan or to waive other costs associated with the insurance plan.
If your plan has these limitations, you will not be eligible for the RUCONEST Patient Savings Program, but you may be eligible for other external needs-based assistance programs. Please contact RUCONEST SOLUTIONS for additional information.
If you have any questions, our team of experts is available to provide assistance. Our priority is your well-being. Please call RUCONEST SOLUTIONS for more information at 1-855-613-4HAE (4423).
