Experience the benefits of one-and-done dosing with RUCONEST

If you are treating the same swell multiple times, speak to your doctor about a change. RUCONEST may be able to help you get back to things that matter. RUCONEST replaces the missing or nonworking C1-INH to stop an HAE swell.
97% or attacks needed just 1 dose of RUCONEST
  • 9 of 10 patients achieved symptom relief in the pivotal clinical trial with just 1 dose (n=44)*
  • In the primary clinical study, patients saw symptom relief in 90 minutes vs 152 minutes with placebo*
  • In the extension study, symptom relief began in 75 minutes*

*50 U/kg (max 4200 U) in clinical studies (open-label extension phase, n=44 [170 attacks]).

RUCONEST offered relief that lasts

Your acute treatment should work with just 1 dose and provide you relief that lasts.
RUCONEST stopped 93% of attacks for at least 3 days
*As shown in a review of studies that included 68 people (280 attacks). Based on a post hoc analysis of pooled data from the randomized controlled study and open-label extension phases of 2 studies involving 127 patients aged 13 years who were treated with RUCONEST 50 U/kg (max 4200 U) for acute attacks of HAE. Data for 72 hours were available for 68 of 127 patients.

RUCONEST has a well-established tolerability profile

RUCONEST has a well-established tolerability profile. Adverse reactions in 2% of patients in 7 studies (all RUCONEST doses up to 100 U/kg) included:

HAE attack symptom: fatigue

Headache9% (19 of 205 patients)

HAE attack symptom: fatigue

Nausea2% (5 of 205 patients)

HAE attack symptom: fatigue

Diarrhea2% (5 of 205 patients)


Just one dose of RUCONEST can get you back to things that matter

  • 97%One and Done – 97% of acute swells were treated with JUST 1 DOSE*
  • 93%Relief That Lasts – Stopped 93% of attacks for at least 3 days
  • 85%Confident Dosing – 85% of patients were confident self-administering

How RUCONEST is helping Sophie manage her swells

*50 U/kg (max 4200 U) in clinical studies (open-label extension phase, n=44 [170 attacks]).
As shown in a review of studies that included 68 people (280 attacks).
Data from 601 patients using RUCONEST show that 85% of patients trained felt confident, mostly confident, or extremely confident on a Likert scale of 1-5 in terms of their ability to self-infuse.

Track your symptoms with the HAE & Me App

The HAE and Me app open on an iPhone.

The HAE & Me app provides free tools to help you stay informed and track your swells.

  • Use the app to accurately track your triggers, swells, and treatment habits.
  • Remember, even if you are on a preventative treatment, many people with HAE may still experience breakthrough swells and it’s important to share these experiences with your doctor.
  • The app creates a comprehensive report you can email to your doctor.
  • Accurately documenting your HAE experience and communicating with your doctor can help ensure you have the right treatment plan for you.

Other app resources include inspirational messages, HAE education, and private medical document storage.

Download on the App Store
Get it on Google Play

Feel empowered

Knowledge is power! Stay informed on the latest in treatment, support, and more.

Preparing for Your Visit

Prepare for a visit with your healthcare provider with this helpful discussion guide.

Patient Support

RUCONEST SOLUTIONS is a program that helps support you throughout your treatment journey.